4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine profile

ID Source	ID
PubMed CID	715538
CHEMBL ID	1454000
CHEBI ID	114956

Synonym
4-[1-(3-methoxy-4-methylbenzyl)-1h-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
smr000021425
MLS000044014 ,
zinc00112082 ,
CHEBI:114956
4-[1-[(3-methoxy-4-methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
MLS002589843
AKOS001727592
STK773910
HMS2340P15
REGID_FOR_CID_715538
[4-[1-(3-methoxy-4-methyl-benzyl)benzimidazol-2-yl]furazan-3-yl]amine
cid_715538
4-[1-[(3-methoxy-4-methyl-phenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
bdbm35511
4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine
CHEMBL1454000
Q27196800
sr-01000092134
SR-01000092134-1
4-{1-[(3-methoxy-4-methylphenyl)methyl]-1h-1,3-benzodiazol-2-yl}-1,2,5-oxadiazol-3-amine
nsc774719
nsc-774719

Class	Description
benzimidazoles	An organic heterocyclic compound containing a benzene ring fused to an imidazole ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, Cruzipain	Trypanosoma cruzi	Potency	31.6228	0.0020	14.6779	39.8107	AID1476
glp-1 receptor, partial	Homo sapiens (human)	Potency	0.8913	0.0184	6.8060	14.1254	AID624417
phosphopantetheinyl transferase	Bacillus subtilis	Potency	89.1251	0.1413	37.9142	100.0000	AID1490
TDP1 protein	Homo sapiens (human)	Potency	3.5094	0.0008	11.3822	44.6684	AID686978; AID686979
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	25.1189	0.0013	18.0743	39.8107	AID926; AID938
67.9K protein	Vaccinia virus	Potency	1.1220	0.0001	8.4406	100.0000	AID720579; AID720580
IDH1	Homo sapiens (human)	Potency	3.6626	0.0052	10.8652	35.4813	AID686970
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	31.6228	0.0103	23.8567	63.0957	AID2662
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	112.2020	0.0501	27.0736	89.1251	AID588590
geminin	Homo sapiens (human)	Potency	5.5303	0.0046	11.3741	33.4983	AID624296; AID624297
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)	Potency	1.5849	0.0580	10.6949	26.6086	AID602310
lamin isoform A-delta10	Homo sapiens (human)	Potency	0.0100	0.8913	12.0676	28.1838	AID1487
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Cathepsin B	Homo sapiens (human)	IC50 (µMol)	44.7826	0.0015	14.1008	45.9741	AID820; AID830
procathepsin L isoform 1 preproprotein	Homo sapiens (human)	IC50 (µMol)	50.0000	0.0016	3.9614	31.1549	AID1627
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (76)

Assay ID	Title	Year	Journal	Article
AID1203438	Cytotoxicity against human SN12C cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203411	Cytotoxicity against human KM12 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203448	Cytotoxicity against human MDA-MB-468 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203444	Cytotoxicity against human MDA-MB-231 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203415	Cytotoxicity against human SNB19 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203432	Cytotoxicity against human SKOV3 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203429	Cytotoxicity against human OVCAR5 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203407	Cytotoxicity against human HCC2998 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203395	Cytotoxicity against human K562 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203430	Cytotoxicity against human OVCAR8 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203414	Cytotoxicity against human SF539 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203384	Antiproliferative activity in sea urchin embryo assessed as antimitotic activity by measuring cleavage arrest exposed for 8 to 20 mins after fertilization and 45 to 55 mins before first mitotic cycle completion measured 2.5 to 5.5 hrs after fertilization	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203404	Cytotoxicity against human NCI-H460 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203394	Cytotoxicity against human HL-60(TB) cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203410	Cytotoxicity against human HT-29 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203439	Cytotoxicity against human TK10 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203398	Cytotoxicity against human SR cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203405	Cytotoxicity against human NCI-H522 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203437	Cytotoxicity against human RXF393 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203424	Cytotoxicity against human UACC257 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203428	Cytotoxicity against human OVCAR4 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203445	Cytotoxicity against human Hs578T cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203433	Cytotoxicity against human 786-0 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203434	Cytotoxicity against human A498 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203386	Antiproliferative activity in sea urchin embryo assessed as destabilization of microtubule by tuberculate eggs after 15 mins to 20 hrs	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203401	Cytotoxicity against human NCI-H226 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203418	Cytotoxicity against human MALME-3M cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203449	Cytotoxicity against human SF295 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203441	Cytotoxicity against human PC3 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203417	Cytotoxicity against human LOXIMVI cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203446	Cytotoxicity against human BT549 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203409	Cytotoxicity against human HCT15 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203442	Cytotoxicity against human DU145 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203400	Cytotoxicity against human HOP62 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203408	Cytotoxicity against human HCT116 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203413	Cytotoxicity against human SF268 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203431	Cytotoxicity against human NCI-ADR-RES cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203385	Antiproliferative activity in sea urchin embryo assessed as destabilization of microtubule by measuring embryo spinning after 15 mins to 20 hrs	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203425	Cytotoxicity against human UACC62 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203447	Cytotoxicity against human T47D cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203443	Cytotoxicity against human MCF7 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203435	Cytotoxicity against human ACHN cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203426	Cytotoxicity against human IGROV1 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203419	Cytotoxicity against human M14 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203422	Cytotoxicity against human SK-MEL-28 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203423	Cytotoxicity against human SK-MEL-5 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203402	Cytotoxicity against human NCI-H23 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203406	Cytotoxicity against human COLO205 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203421	Cytotoxicity against human SK-MEL-2 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203393	Cytotoxicity against human CCRF-CEM cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203387	Cytotoxicity against human NCI60 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203420	Cytotoxicity against human MDA-MB-435 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203399	Cytotoxicity against human A549 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203427	Cytotoxicity against human OVCAR3 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203412	Cytotoxicity against human SW620 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203416	Cytotoxicity against human U251 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203383	Antiproliferative activity in sea urchin embryo assessed as antimitotic activity by measuring cleavage alteration exposed for 8 to 20 mins after fertilization and 45 to 55 mins before first mitotic cycle completion measured 2.5 to 5.5 hrs after fertilizat	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203381	Cytotoxicity against human SNB75 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203382	Cytotoxicity against human HOP92 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203397	Cytotoxicity against human RPMI8226 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203440	Cytotoxicity against human UO31 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203396	Cytotoxicity against human MOLT4 cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1203403	Cytotoxicity against human NCI-H322M cells	2015	European journal of medicinal chemistry, Apr-13, Volume: 94	A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (16.67)	29.6817
2010's	4 (66.67)	24.3611
2020's	1 (16.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
colchicine (S)-colchicine : A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions.	2.11	1	alkaloid; colchicine	anti-inflammatory agent; gout suppressant; mutagen
vinblastine [no description available]	2.11	1
4-[1-[(3-methoxyphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine [no description available]	2.11	1	benzimidazoles

Condition	Indicated	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	0	2.05	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	2.05	1	0

4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine

Cross-References

Synonyms (23)

Drug Classes (1)

Protein Targets (14)

Potency Measurements

Inhibition Measurements

Bioassays (76)

Research

Studies (6)

Market Indicators

Research Demand Index: 12.35

Study Types

4-[1-[(3-methoxy-4-methylphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amine

Cross-References

Synonyms (23)

Drug Classes (1)

Protein Targets (14)

Potency Measurements

Inhibition Measurements

Bioassays (76)

Research

Studies (6)

Market Indicators

Research Demand Index: 12.35

Study Types

Related Drugs (3)

Related Conditions (2)